Bacterial pathogenesis and mediators in apical periodontitis

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Bacterial pathogenesis and mediators in apical periodontitis.

Apical periodontitis is a group of inflammatory diseases caused by microorganisms (mainly bacteria) infecting the necrotic root canal system. The pathogenesis of different types of apical periodontitis and even the same type in different individuals is unlikely to follow a stereotyped fashion with regard to the involved bacterial mediators. Disease pathogenesis is rather complex and involves a ...

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Inflammatory mediators in the pathogenesis of periodontitis.

Periodontitis is a chronic inflammatory condition of the periodontium involving interactions between bacterial products, numerous cell populations and inflammatory mediators. It is generally accepted that periodontitis is initiated by complex and diverse microbial biofilms which form on the teeth, i.e. dental plaque. Substances released from this biofilm such as lipopolysaccharides, antigens an...

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Pathogenesis of Apical Periodontitis: a Literature Review

OBJECTIVES This review article discusses the host response in apical periodontitis with the main focus on cytokines, produced under this pathological condition and contributing to the degradation of periradicular tissues. The pace of research in this field has greatly accelerated in the last decade. Here we provide an analysis of studies published in this area during this period. MATERIAL AND...

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a review of novel bacterial complex lipids: implications for the pathogenesis of apical periodontitis

the importance of the role played by bacteria in the pathogenesis of pulpal and apical disease has been established. one of the characteristics of apical periodontitis is apical bone resorption, which is due to apical immune response to bacterial infection. recently, novel bacterial complex lipid called phosphorylated dihydroceramides has been discovered to be of inflammatory activators. the ba...

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A Review of Novel Bacterial Complex Lipids: Implications for the Pathogenesis of Apical Periodontitis

The importance of the role played by bacteria in the pathogenesis of pulpal and apical disease has been established. One of the characteristics of apical periodontitis is apical bone resorption, which is due to apical immune response to bacterial infection. Recently, novel bacterial complex lipid called phosphorylated dihydroceramides has been discovered to be of inflammatory activators. The ba...

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ژورنال

عنوان ژورنال: Brazilian Dental Journal

سال: 2007

ISSN: 0103-6440

DOI: 10.1590/s0103-64402007000400001